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Middle Patch 16.19.1 op.gg
Cassiopeia Build
Latest Cassiopeia build for League of Legends with items, runes, summoner spells, skill order, counters and patch data.
48.13% Win Rate 1.35% Pick Rate 6,081 Games
Cassiopeia Build Guide
Cassiopeia’s mid lane numbers read 48.88% winrate at a 1.4% pick rate on patch 16.13.1, a demanding pick per current ranked data, though top lane is listed as a secondary option for those willing to adapt. Deathfire Touch is her keystone, adding damage over time to her poison-stacking combos.
Skill order runs E first, then Q, then W, prioritizing twin fang’s poison application. Tear of the Goddess, Rod of Ages, and Seraph’s Embrace make up her core, a mana-scaling build that grows her damage and bulk together. See the complete item order, runes, and counters below.
Cassiopeia Build
C Current tier: C Top — view tier list
Imported from op.gg · updated every 48 hours · last update Sep 25, 2026.
Starting Items
Core Items
Boots
Full Item Set
Cassiopeia Runes — Sorcery + Precision
Deathfire Touch 
Manaflow Band 
Transcendence 
Scorch 
Presence of Mind 
Coup de Grace 
Adaptive Force Adaptive Force 
Health Scaling Cassiopeia Summoner Spells
Flash 
TeleportCassiopeia Skill Order
E › Q › W
Ability Order by Level
1E 2Q 3W 4E 5E 6R 7E 8Q 9E 10Q 11R 12Q 13Q 14W 15W
Levels shown as recorded in ranked data; R is highlighted at its level-up points.
Starting Items
Core Items
Boots
Full Item Set
Cassiopeia Runes — Sorcery + Precision
Deathfire Touch Manaflow Band Transcendence Scorch Presence of Mind Coup de Grace Adaptive Force Adaptive Force Health Scaling Cassiopeia Summoner Spells
Flash 
IgniteCassiopeia Skill Order
E › Q › W
Ability Order by Level
1E 2Q 3W 4E 5E 6R 7E 8Q 9E 10Q 11R 12Q 13Q 14W 15W
Levels shown as recorded in ranked data; R is highlighted at its level-up points.
Cassiopeia Counters
Weak Against
39.9% 228 games 
40.7% 113 games 
42.3% 104 games 
44.0% 109 games 
45.4% 119 games Strong Against
54.4% 103 games 
53.8% 173 games 
53.6% 112 games 
53.0% 149 games 
52.0% 123 games Win rates are Cassiopeia's results against each champion, imported from op.gg.
Cassiopeia Build FAQ
Based on current ranked data (op.gg, patch 16.19.1), the strongest recorded Cassiopeia build in Middle goes Tear of the Goddess, Rod of Ages, Seraph's Embrace, Rylai's Crystal Scepter as core items, with a 48.13% win rate across 6,081 games.
The most played rune page runs Deathfire Touch (Sorcery) with Precision as the secondary tree.
Tear of the Goddess, Rod of Ages, Seraph's Embrace, Rylai's Crystal Scepter.
Based on real matchup data, Cassiopeia struggles most against Syndra, LeBlanc, Ekko.
Build and counter data is refreshed automatically every 48 hours from ranked game statistics.
